Maddi Sunshine
Dr. Boyd
Biology 1-2 Honors
Bone Marrow Cells Migrate to Tumors and Can Slow Their Growth
Summary:
Bone marrow- derived cells also known as BMDC’s are part of the growth in the spread of tumors mainly to the breast, lung, brain, and stomach. To test the role of BMDC’s researchers created a mouse model that could be used to track the cells moving while tumors formed. Their results suggested that
“More effective cancer treatments may be developed by exploiting the mechanism by which bone marrow cells migrate to tumors and retard their proliferation” ScienceDaily
During the experiment the first group of mice which had the fluorescence genes were donors of the bone marrow. The second groups were injected with the donated marrow. Colon cancer cells were later injected into the same mice and tumors formed within 3 weeks.
Critique & Impact:
This is important for people to know because when cancer is in the bone marrow it is very likely to spread to more places quickly. Doctors say that with this new knowledge they hope to make new treatments that can help them overcome the cancer.
Reference: www.sciencedaily.com/releases/2011/10/111007103312.htm
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